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Corneal Health

İzmir Keratoconus Surgery

Keratoconus is a condition in which the transparent corneal layer at the front of the eye gradually thins, changes shape, and bulges forwards into a cone. This structural change may adversely affect visual quality by causing irregular astigmatism and myopia. The condition is often detected during adolescence or young adulthood and may occur at different […]

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Keratoconus Surgery

Keratoconus is a condition in which the transparent corneal layer at the front of the eye gradually thins, changes shape, and bulges forwards into a cone. This structural change may adversely affect visual quality by causing irregular astigmatism and myopia. The condition is often detected during adolescence or young adulthood and may occur at different levels of severity in both eyes. Frequent changes in spectacle prescription, blurred vision, and light scatter are among the notable symptoms. The treatment plan is determined according to corneal thickness, the rate of disease progression, and the person's visual needs. Procedures referred to as keratoconus surgery aim to control the course of the condition or support visual quality. Surgery may not be necessary for every patient, and the appropriate approach is selected following a detailed assessment.

What Causes Keratoconus?

Keratoconus is associated with changes in the connective tissue that provides the cornea with its strength. Genetic predisposition, family history, eye allergies, and the habit of continuously rubbing the eyes may contribute to the development or progression of the condition. Frequent and forceful rubbing of the eyes, particularly due to allergies, creates repeated mechanical pressure on the cornea. Certain connective tissue disorders and other eye conditions are also taken into consideration during the assessment. However, a specific cause may not be identified in every patient. The severity of the condition may not be the same in both eyes, and changes in one eye may be noticed earlier. Early diagnosis is important for monitoring progression and planning the necessary measures in a timely manner.

What Is Keratoconus Surgery?

Keratoconus surgery is a general term for procedures intended to address problems caused by the progressive thinning and irregularity of the cornea. This definition does not refer to a single surgical method but covers procedures performed for different purposes. Corneal cross-linking treatment is primarily intended to slow or stop the progression of the condition. Intracorneal ring segments aim to make the shape of the cornea more regular and support visual rehabilitation in suitable patients. In advanced stages, a corneal transplant may be considered if there is significant scarring or advanced thinning. Additional methods, such as limited surface laser treatment or a phakic intraocular lens, may also be considered in selected patients. The method is selected according to the stage of the condition, corneal measurements, and the current level of vision.

How Is the Treatment Plan Determined?

When planning keratoconus treatment, visual acuity, spectacle prescription, and the structural characteristics of the cornea are assessed together. Corneal topography and tomography show the curvature, anterior and posterior surface characteristics, and thickness distribution of the cornea. Consecutive measurements are compared to determine whether the condition is progressing. The value at the thinnest point of the cornea, the presence of surface scarring, and tolerance of contact lens use also affect the decision-making process. In the early stages, visual support with glasses or specialist contact lenses may be sufficient. When progression is detected, treatments intended to strengthen the cornea may take priority. If visual quality has deteriorated significantly, options such as ring segments, selected additional procedures, or transplantation at an advanced stage are considered. The aim of treatment is not the same for every patient, and procedures may be performed in a specific sequence when necessary.

How Is Corneal Cross-Linking Performed?

Corneal cross-linking is a treatment intended to increase the structural strength of the cornea. During the procedure, drops containing vitamin B2, known as riboflavin, are applied to the cornea, followed by controlled ultraviolet A light. This application helps strengthen the bonds between the collagen fibres in the cornea. The main objective is to help prevent further thinning and steepening of the cornea over time in progressive keratoconus. The procedure is generally performed under topical anaesthesia, and the treatment time may vary according to the protocol used. Cross-linking is not a procedure that increases visual acuity or eliminates the need for glasses in every patient. As the shape of the cornea may change over time after treatment, the results are monitored with regular measurements. The risk of progression and the characteristics of the cornea are assessed together when determining whether treatment is necessary.

Epi-Off and Epi-On Methods

In the epi-off cross-linking method, the outermost epithelial layer of the cornea is removed in a controlled manner before the procedure. This facilitates the penetration of riboflavin into the corneal tissue, and light is applied according to the planned protocol. Pain, stinging, sensitivity to light, and temporary blurred vision may occur while the epithelium heals. In the epi-on method, the epithelium is preserved, and different applications are used to support the penetration of riboflavin into the tissue. This approach may reduce post-procedure discomfort in some patients, but its effectiveness may vary according to the method used and the characteristics of the cornea. In accelerated cross-linking protocols, the duration and intensity of light exposure may be adjusted differently. The appropriate approach is determined according to the degree of progression, corneal thickness, ocular surface health, and clinical assessment. The potential benefits and limitations of each technique should be assessed in detail before the procedure.

Treatment Approach for Thin Corneas

Corneal thickness is one of the main assessment criteria when planning cross-linking treatment. In standard epi-off protocols, it is important for the cornea to have sufficient thickness during ultraviolet light exposure to protect the deeper structures of the eye. In some standard applications, 400 microns is one of the thresholds used in safety assessments. However, this value should not be interpreted in the same way for every method and every patient. For thinner corneas, special solutions or modified protocols designed for thin corneas may be considered in suitable patients. The suitability of these options depends on the actual structure of the cornea, measurements taken during the procedure, and the conditions of application. Alternative treatment methods may be considered for corneas that are excessively thin, significantly scarred, or considered unsuitable for the procedure. A definitive decision on suitability is therefore not based on a single thickness measurement alone.

Intracorneal Ring Treatment

Intracorneal ring treatment is based on placing small, semicircular segments within the corneal tissue. Also known as intrastromal corneal ring segments, these implants aim to reduce central corneal curvature and irregularity. The segments are placed into channels created within the cornea either mechanically or with the assistance of a femtosecond laser. The number, size, and position of the ring segments are planned by taking corneal mapping and the distribution of the condition into account. This method may be considered in selected cases, particularly when adequate vision cannot be achieved with glasses or contact lens use is difficult. Ring treatment does not stop the progression of keratoconus on its own and does not replace cross-linking. In progressive disease, the two methods may be performed together or at different times according to the patient's condition. The rings can be removed or replaced when necessary, although this requires further assessment and may involve an additional procedure.

Can Laser Treatment Be Performed for Keratoconus?

Standard LASIK and similar refractive laser procedures that thin the cornea are generally unsuitable for eyes with keratoconus. These methods may further reduce the structural strength of an already weakened cornea and cause the condition to worsen. However, limited topography-guided surface laser treatment intended to reduce irregularities on the corneal surface may be considered in selected patients. This approach is generally planned together with corneal cross-linking or after corneal stability has been achieved. Corneal thickness, the amount of tissue to be removed, the existing irregularity, and the progression status of the condition are considered when assessing suitability. The aim may not always be to eliminate the spectacle prescription completely but to regularise the corneal surface to a certain extent. Not every patient with keratoconus is suitable for laser treatment, and in some cases laser treatment should not be performed at all. The decision to proceed is made by assessing the potential benefit together with the additional risk to the cornea.

Which Patients Are Suitable for a Phakic Lens?

A phakic intraocular lens is a surgical method in which an additional lens is placed inside the eye while preserving the natural lens. In patients with keratoconus, this approach is not a direct treatment for the condition but is considered an additional option for correcting refractive error in selected cases. It must first be demonstrated that the progression of keratoconus has been stopped or that the condition has remained stable for a long period. The anterior chamber depth, corneal endothelial cells, and other internal structures of the eye are also examined in detail. A phakic lens may not provide a sufficient improvement in vision for every patient with significant irregular astigmatism. This method does not treat corneal thinning or bulging on its own. As there are risks associated with intraocular surgery, the potential benefits and limitations are assessed individually. When necessary, its relationship with cross-linking or other corneal treatments is planned separately.

Corneal Transplantation in Advanced Keratoconus

Corneal transplantation is a surgical option considered in advanced keratoconus when adequate vision cannot be achieved with other methods. Significant corneal scarring, advanced thinning, or vision loss that cannot be corrected with contact lenses may indicate the need for transplantation. In deep anterior lamellar keratoplasty, the anterior layers of the cornea are replaced while an attempt is made to preserve the patient's own inner layer. In penetrating keratoplasty, the full thickness of the cornea is replaced, and the appropriate method is determined according to the condition of the cornea. Recovery after transplantation may take longer than with other keratoconus procedures. Monitoring the sutures, using eye drops regularly, and observing the corneal tissue are important parts of this process. Risks such as graft rejection, infection, astigmatism, and changes in intraocular pressure are assessed for each patient. Some patients may still need glasses or specialist contact lenses after transplantation.

When Is Treatment Necessary?

The timing of keratoconus treatment is determined according to whether the condition is progressing and how it affects vision. An increase in corneal curvature, a reduction in thickness, or a significant change in spectacle prescription is assessed for signs of progression. As changes may occur more rapidly in younger patients, follow-up intervals may be adjusted individually. In progressive keratoconus, cross-linking may be considered to support the structural strength of the cornea. Ring segments may be considered in patients with suitable corneal structures who cannot achieve adequate vision with glasses or contact lenses. Different surgical options may be needed when the primary cause of vision loss is corneal scarring or advanced structural deterioration. If the condition is stable and vision can be supported with suitable aids, regular monitoring may be sufficient. Early presentation allows the treatment decision to be based not only on visual symptoms but also on changes demonstrated by measurements.

Who Is Not Suitable for Treatment?

Cross-linking and intracorneal ring procedures may not be suitable for every patient with keratoconus. Active eye infection, significant corneal scarring, severe ocular surface disorder, and advanced dry eye are assessed separately before the procedure. If the cornea is not sufficiently thick for the standard treatment, it may be necessary to modify the technique or consider other options. People with a history of herpes keratitis undergo a special assessment because of the risk of reactivation. Cross-linking is generally postponed during pregnancy, and the monitoring plan is arranged according to the individual's circumstances. Immune system disorders, current medicines, and conditions that affect wound healing are also considered in the decision-making process. Intracorneal rings may be unsuitable if there is insufficient tissue at the implantation site or advanced scarring. Advanced keratoconus, active inflammation, and accompanying eye conditions may limit the expected benefit of the rings. The decision on suitability is based on an assessment of the entire structure of the eye, not on a single diagnosis or measurement.

Preoperative Preparation

A detailed eye examination and corneal imaging are performed before keratoconus treatment. Corneal topography, tomography, and thickness measurements help determine the stage and progression status of the condition. Spectacle prescription, corrected visual acuity, and signs of allergy or dryness on the ocular surface are also assessed. If contact lenses are used, the patient may be asked to stop wearing them for a specified period to prevent them from affecting the corneal measurements. The duration of this period varies according to the type of lens used and the condition of the cornea. When ring treatment is planned, the area where the segments will be placed, the thickness distribution, and the location of the corneal irregularity are examined separately. If cross-linking is to be performed, the treatment protocol is selected by taking corneal thickness and the condition of the epithelium into account. Regularly used medicines, previous eye conditions, and the possibility of pregnancy should be disclosed before the procedure. The purpose of the preparation process is to determine the appropriate individual approach and reduce potential risks.

Recovery After Treatment

Recovery after keratoconus treatment varies according to the method used and the condition of the corneal surface. Pain, stinging, watering, and sensitivity to light may occur during the first few days after epi-off cross-linking. The bandage contact lens placed to protect the cornea is removed during a follow-up examination according to the healing of the epithelium. Vision may be blurred initially and may fluctuate over the following weeks as the cornea recovers. A foreign-body sensation, temporary fluctuations in vision, and sensitivity to light may also occur after intracorneal ring implantation. The effects of the rings and changes in the corneal surface are monitored for a specified period. Recovery and stabilisation of vision may take longer after a corneal transplant. For each method, the follow-up dates, duration of eye drop use, and time for returning to daily activities are arranged according to the individual's condition.

What Should Be Considered After Surgery?

Prescribed eye drops should be used for the recommended duration and at the recommended frequency after treatment. The schedule for antibiotic drops or drops intended to control inflammation is determined according to the procedure performed and the healing findings. Particularly during the first few days, the eye should not be rubbed or subjected to pressure, and contact with contaminated water should be avoided. The appropriate time to resume swimming, eye make-up, strenuous physical activity, and contact lens use is assessed during the follow-up examination. Wearing sunglasses outdoors may help reduce sensitivity to light. Controlling allergy-related itching is important for preventing the continued habit of rubbing the eyes. If worsening pain, increasing redness, significant discharge, or sudden loss of vision develops, prompt assessment is required. Epithelial healing, corneal clarity, ring position, and intraocular pressure where necessary are monitored during follow-up appointments. Long-term follow-up helps detect changes in the course of the condition in a timely manner.

Possible Side Effects and Risks

The side effects that may occur with keratoconus treatments vary according to the method selected. Temporary pain, sensitivity to light, blurred vision, and temporary corneal haze may occur after cross-linking. Delayed epithelial healing, infection, permanent scarring, or reduced visual quality are potential problems that require more detailed follow-up. If the cornea is excessively thin, ultraviolet light exposure may pose a risk to deeper tissues when appropriate safety conditions are not met. Although surface discomfort may be more limited with the epi-on method, the expected degree of corneal strengthening may not be the same in every patient. Continued progression of the condition is also one of the situations that should be monitored after treatment. The risks vary according to the structure of the cornea, accompanying conditions, selected protocol, and aftercare process. An individual risk assessment before the procedure and regular follow-up afterwards are important.

With intracorneal ring treatment, the segment may move, approach the surface, become exposed, or an infection may develop. Some patients may experience halos around lights at night, glare, or fluctuations in vision. Failure of the cornea to become as regular as expected or the development of scarring around the ring are also possible outcomes to be assessed. If necessary, an additional procedure may be planned to reposition, replace, or remove the ring segments. After corneal transplantation, graft rejection, infection, suture-related problems, and changes in intraocular pressure are monitored. With intraocular procedures such as a phakic lens, the effects on corneal endothelial cells, intraocular pressure, and the natural lens are assessed separately. It is not possible to eliminate the risk of complications completely with any surgical procedure. Treatment is therefore selected not only according to the potential improvement in vision but also according to procedural risks and the need for long-term follow-up.

How Is Treatment Success Assessed?

The success of keratoconus treatment is assessed according to the main objective of the method used. With cross-linking, the primary criterion is whether disease progression has been brought under control by monitoring corneal curvature and thickness over time. Although visual acuity may improve, this outcome is not expected or guaranteed for every patient. With intracorneal ring treatment, regularisation of the corneal surface, corrected vision with glasses, and tolerance of contact lens use are important. After corneal transplantation, the assessment is based on the clarity of the tissue, the healing process, and the level of vision achieved. The initial stage of the condition, corneal scarring, accompanying eye problems, and the person's age may affect the results. A continued need for glasses or specialist contact lenses after treatment does not necessarily mean that the procedure has failed. To establish realistic expectations, the objective of treatment and individual limitations should be assessed clearly before the procedure.

Can the Condition Progress After Treatment?

Although cross-linking aims to strengthen the cornea in progressive keratoconus, the same level of response may not be achieved in every patient. Young age, advanced corneal irregularity, significant thinning, and continued eye rubbing are particularly important for follow-up. Failure to control allergies or an inadequate corneal response to treatment may require an assessment of progression. This does not necessarily mean that the treatment has been ineffective and is investigated through repeated measurements. Intracorneal rings are intended to regularise the shape of the cornea and do not stop the biological progression of the condition on their own. The need for cross-linking may therefore also be considered separately in an eye that has received ring segments. Corneal topography, thickness measurements, and visual acuity are compared during follow-up examinations. If progression is detected, additional treatment, reassessment, or a different approach may be planned. Long-term follow-up for keratoconus requires a more comprehensive care process than assessment of the outcome of a single procedure.

Use of Glasses and Contact Lenses

Glasses and contact lenses have an important role in supporting visual quality in keratoconus treatment. In the early stages, adequate vision may be achieved with glasses, but their effectiveness may decrease as corneal irregularity increases. Rigid gas-permeable lenses, hybrid lenses, or scleral lenses may help reduce the effect of corneal surface irregularity on vision. These lenses are selected according to the shape of the cornea, the ocular surface, and the person's wearing habits. Contact lenses may correct vision, but they do not stop the progression of keratoconus. Glasses or specialist contact lenses may still be required after cross-linking or ring treatment. In some patients, the lens parameters need to be adjusted because of changes in the shape of the cornea. Proper cleaning of the lenses, adherence to wearing times, and regular follow-up are important for eye health.

Keratoconus Surgery and Follow-Up in İzmir

When planning keratoconus surgery in İzmir, the stage of the condition, corneal topography, and previous treatments are assessed together. During the examination, corneal thickness, the degree of irregular astigmatism, and visual acuity are examined in detail. Cross-linking, intracorneal rings, specialist contact lenses, or corneal transplantation when necessary are considered according to the individual's findings. The same procedure is not required for every patient, and in some cases regular monitoring alone may be sufficient. The post-treatment follow-up programme is prepared according to the method used and the healing characteristics of the cornea. For people researching keratoconus treatment in İzmir and the Konak area, the appropriate approach is to assess detailed examination findings and corneal measurements before focusing on the name of a procedure. The person's daily life and visual needs are considered when planning treatment, as is the risk of disease progression.

Keratoconus Surgery Prices

Keratoconus surgery prices may vary according to the stage of the condition and the treatment method planned. Cross-linking, intracorneal rings, phakic lenses, and corneal transplantation require different preparation, treatment, and follow-up processes. Whether the procedure is planned for one or both eyes, the materials to be used, and any necessary additional assessments may also affect the process. When researching keratoconus surgery prices in 2026, an individual cost cannot be determined by considering the name of the procedure alone. Whether the planned method is actually necessary is established by assessing corneal measurements and examination findings. Personalised pricing information can therefore be provided once the treatment plan has been clarified. You can contact the clinic through the website to obtain information about the examination process and suitable treatment options.

FREQUENTLY ASKED QUESTIONS

What You Need to Know About Keratoconus Surgery

What are the symptoms of keratoconus?

Symptoms of keratoconus usually begin during adolescence or young adulthood and may progress over a period of 10 to 20 years. Common symptoms include blurred or distorted vision, increased sensitivity to light and glare, difficulty seeing at night, frequent changes in spectacle prescription, and headaches associated with eye pain. In advanced stages, sudden visual disturbances or blurring may develop. The condition generally affects both eyes, but symptoms may differ between them. Keratoconus is a rare condition that affects 1 in 2,000 people, although some estimates suggest that it occurs in 1 in 400 people. It affects men and women equally and is more common in non-Caucasian populations. The risk is higher in people with a family history of keratoconus. Factors such as eye rubbing, allergies, asthma, and eczema may also increase the risk of developing the condition. Early diagnosis and treatment are important for slowing its progression and preserving visual quality.

What is the success rate of cross-linking treatment?

The success rate of corneal collagen cross-linking (CXL) for keratoconus ranges from 70% to 95%. Various studies have reported that keratoconus progression stops and visual acuity improves in 70% to 90% of patients following treatment. Success rates of up to 95% have been reported, particularly with epi-off CXL treatment.

Who is suitable for corneal ring treatment?

Corneal ring procedures for keratoconus may be suitable for patients who experience vision loss that cannot be corrected with glasses or contact lenses and who have a clear central cornea and stable refraction. However, corneal rings do not stop the progression of the condition and may not be effective in progressive keratoconus. This treatment may not be suitable for patients who have good visual function or whose condition is progressing.

How long does visual improvement take after keratoconus treatment?

The time required for vision to improve after keratoconus treatment varies according to the treatment performed. With corneal cross-linking (CXL), it may take several years for improvements in vision to become fully apparent because visual acuity gradually improves and stabilises after treatment. With treatments such as intrastromal corneal ring segments or toric implantable collamer lenses (TICL), significant visual improvements may be seen within one year, with both corrected vision and visual acuity improving considerably. Some treatments may therefore provide faster improvement, while visual recovery after treatments such as CXL may extend over several years.

Does keratoconus progress if left untreated?

Yes, keratoconus may progress if left untreated. Studies have shown that within one year, the steepest keratometry value (Max-K) increased in 6.6% of untreated eyes, visual acuity decreased in 3.2%, and the thinnest corneal thickness (TCT) decreased in 3.1%. Younger patients and those with a steeper initial Max-K reading have a higher risk of progression. Each additional dioptre increases the risk of deterioration in visual acuity by 7% and the risk of TCT thinning by 3%. Each year of younger age increases the risk of Max-K becoming steeper by 4% and the risk of TCT thinning by 2%.

Which doctor should I consult for keratoconus surgery?

You should consult an ophthalmologist for keratoconus surgery. These specialists are trained in this particular condition affecting the corneal layer of the eye. The decision regarding surgery and the appropriate method is made by your doctor following a detailed eye examination. An ophthalmologist experienced in corneal conditions or refractive surgery will provide you with the most appropriate information and treatment options. Early diagnosis and appropriate treatment aim to preserve and improve visual quality. Do not worry. Specialists are available to help you with this condition.

How long does keratoconus surgery take?

Corneal cross-linking (CXL) performed for keratoconus generally takes between 30 and 60 minutes. Other surgical options include ring implantation and corneal transplantation. These procedures may also take between approximately 30 minutes and one hour.

Which department or doctor should I consult for keratoconus?

For the diagnosis and treatment of keratoconus, you should consult the Department of Ophthalmology. Follow-up and treatment should be provided by an ophthalmologist specialising in corneal conditions.

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